EPSRC Centre for Doctoral Training in Advanced Therapeutics and Nanomedicines

University of Nottingham
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Karolina Dziemidowicz

CDT student, UCL School of Pharmacy



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Current Research

PhD Project Title: Microparticles for Enhancing Adoptive T Cell Therapy for Cancer

Supervisor: Dr Gareth Williams

Project description: This PhD project investigates a novel approach for adoptive cell therapy that involves using biodegradable, biocompatible TIPS microparticles to stimulate a targeted, tumour-specific effector response and expansion of T cells in the immunosuppressive tumour microenvironment. If successful, the proposed technology will provide a step-change for adoptive cell therapy by improving tumour immunity and reducing the risk of toxicities that arise from on-target/off-tumour cross reactivity. The first part of the project focuses on the particle design, fabrication and characterisation.


Bowles BJ, Dziemidowicz K, Lopez FL, Orlu M, Tuleu C, Edwards AJ, Ernest TB (2018) Co-Processed Excipients for Dispersible Tablets–Part 1: Manufacturability,  AAPS PharmSciTechDOI: 10.1208/s12249-018-1090-4.

Dziemidowicz K, Lopez FL, Bowles BJ, Edwards AJ, Ernest TB, Orlu M, Tuleu C (2018) Co-Processed Excipients for Dispersible Tablets–Part 2: Patient Acceptability, AAPS PharmSciTech; DOI: 10.1208/s12249-018-1104-


EPSRC Centres for Doctoral Training in Advanced Therapeutics and Nanomedicines


The University of Nottingham
School of Pharmacy
Boots Science Building
University of Nottingham,
Nottingham, NG7 2RD
t: +44(0)115 823 2121
e: Claudia.Matz@nottingham.ac.uk

University College London
School of Pharmacy
University College London
29-39 Brunswick Square,
London WC1N 1AX.
t: +44 (0) 20 7753 5948
e: s.marks.pharm@ucl.ac.uk